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SHODEX: Better Multivitamins Analysis with Polymer Columns ODP, NH2P

news | 20 September 2021
Tag: indonesia shodex thailand vitamin e

Are you seeking better column lifetime than C18 for Vitamin A, Vit D, Vit E, Vit K analysis?
Or not satisfied with separation by reversed phase for Vitamin B and Vit C analysis?

Shodex™ is a specialist for high-quality polymer-based columns with long lifetime (Reversed Phase RP, HILIC, SUGAR, GPC). In This article we’d like to introduce our Reversed Phase and HILIC Polymer column for multivitamin analysis application.

1) Fat-Soluble Vitamins
Asahipak ODP-50 4E [USP L67] reversed phase mode was used for the simultaneous analysis of fat-soluble vitamins. Good calibration curves were obtained for them.

Sample : 20 μL
1. Vitamin K3 1.5μg/mL
2. Vitamin A 1.0IU/mL(0.3μg/mL)
3. Vitamin A acetate 0.5IU/mL(1.9μg/mL)
4. Vitamin D2 13.2IU/mL(0.3μg/mL)
5. Vitamin D3 13.2IU/mL(0.3μg/mL)
6. Vitamin E acetate 2.4μg/mL
7. Vitamin E 2.5μg/mL
8. Vitamin K1 2.4μg/mL

Column : Shodex Asahipak ODP-50 4E (4.6 mm I.D. x 250 mm) 
Eluent : CH3CN/CH3OH = 50/50
Flow rate : 0.6 mL/min
Detector : UV (280 nm)
Column temp. : 30 °C

2) Food Containing Vitamins
Vitamins in food were analyzed using RSpak DE-413 [USP L71), a column for reversed phase chromatography.

(Sample pretreatment)
– Dissolve 80mg of the food containing vitamins in 12mL of the eluant (A).
– Pass through a 0.45μm filter before injecting into HPLC.

Sample : 20 μL
1. Vitamin C 145μg/mL
2. Vitamin B6 21.2μg/mL
3. Vitamin B2 7.3μg/mL

Column : Shodex RSpak DE-413 (4.6 mm I.D. x 150 mm) 
Eluent : (A); 1/30M Potasium phosphate buffer (pH 6.8) / CH3CN = 98/2
               (B); H2O / CH3CN = 50/50
                Gradient: 0 min to 4 min, 100% (A), 4 min to 15 min, 100% (A) to 30% (A), After 15 min, 30% (A)
Flow rate : 0.6 mL/min
Detector : UV (254 nm)
Column temp. : 35 °C

3) Water-Soluble Vitamins
To those who are not satisfied with RP mode for water-soluble vitamins, NH2P-50 4E [USP L82] offers ion exchange chromatography. Six water-soluble vitamins were separated within 5 minutes.

[Note] This analysis requires column equilibration.
For column equilibration: First introduce 60 mM phosphoric acid at 0.5 mL/min for 2 hours, and then switch to the eluent.

Sample : 20 μL
1. Vitamin B6 50μg/mL
2. Nicotinamide 10μg/mL
3. Vitamin B12 10μg/mL
4. Nicotinic acid 10μg/mL
5. Folic acid 10μg/mL
6. Vitamin C 10μg/mL

Column : Shodex Asahipak NH2P-50 4E (4.6 mm I.D. x 250 mm) 
Eluent : 40 mM H3PO4 aq./CH3CN = 45/55
Flow rate : 1.0 mL/min
Detector : UV (254 nm)
Column temp. : 40 °C

Please do not hesitate to contact us for further information and demo column availability.

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SHODEX Chromato News September 2021

news | 14 September 2021
Tag: chromatonews shodex

New Application Data on Shodex.com

★ Analysis of Urea, an Impurity in Fluorouracil Injection Proposed in USP-NF Pharmacopeial Forum (SB-802.5 HQ) >> Application Note

☆ Analysis of Enoxaparin Sodium (KW-803 + KW-802.5) >> Application Note

★ Analysis of Meglumine (YS-50) >> Application Note

☆ Analysis of Meglumine (NN-814) to replace NN-414 >> Application Note

Contact us today for your free, no-obligation technical consultation and demo offer.

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Showa Denko Installs Additional Lines to Produce Aluminum Heat Radiators for xEVs

news | 01 September 2021
Tag: automotive

Showa Denko K.K. (SDK) (Tokyo: 4004) has decided to double Oyama Plant’s capacity to produce aluminum heat radiators for power modules (PMs)*1 to be installed in electrified vehicles (xEVs) including battery electric vehicles, hybrid vehicles and plug-in hybrid vehicles, in order to respond to an increase in demand for aluminum heat radiators for PMs. SDK has started installation of the additional production line whose start-up of operation is scheduled to be at the beginning of 2022.

PMs are important parts of xEVs and contribute to the improvement in the performance of xEVs. For example, PMs contribute to extension of cruising range and improvement in fuel economy of cars. PMs are usually installed into limited spaces of xEVs. Therefore, heat radiators for PMs must be small, be designed to allow various installation methods, and have high energy efficiency and large heat dissipation capacity.

Aluminum heat radiators for PMs produced by SDK adopt direct vacuum brazing*2 between insulated substrates and other parts including aluminum fins produced by SDK. Therefore, SDK’s aluminum heat radiators for PMs are small, have large heat dissipation capacity, and allow free design of coolant pipes, thereby having a multiplicity of uses. SDK started to produce aluminum heat radiators for PMs in 2019. SDK’s aluminum heat radiators are put into PMs by a large PM manufacturer in Japan, and those PMs are installed in xEVs assembled by various car manufacturers operating in Japan and other Asian countries.

Aluminum heat radiator for PM

Backed by the global movement toward realization of carbon neutral society, the automobile industry is accelerating its shift toward xEVs. Therefore, the market for aluminum heat radiators for PMs is expected to expand further. SDK will develop and produce smaller high-performance aluminum heat radiators for PMs on the basis of its long-time fostered aluminum-alloy design technology, aluminum processing technology and power-module evaluation technology, and provide customers with solutions for their problems, thereby expanding its aluminum specialty components business.

*1. Power module (PM) is a part of electronic device. It consists of several power semiconductor chips, and supplies electronic power to an electronic device. PM with good efficiency improves xEVs’ performance.
*2. Vacuum brazing joints parts without melting basic materials. Vacuum brazing is suitable for jointing of precision parts because inside of the furnace is vacuum and fine control of inside temperature is possible.

This news originally published on www.sdk.co.jp 

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